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In this paper, we will consider three deterministic models for the study of the interaction between the human immune system and a virus: the logistic model, the Gompertz model, and the generalized logistic model (or Richards model). A qualitative analysis of these three models based on dynamical systems theory will be performed by studying the local behavior of the equilibrium points and obtaining the local dynamics properties from the linear stability point of view. Additionally, we will compare these models in order to understand which is more appropriate to model the interaction between the human immune system and a virus. Some natural medical interpretations will be obtained, which are available for all three models and can be useful to the medical community.
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The industrial sector is one of the key sectors for the Turkish economy in terms of production, employment and exports. The volatility in the exchange rate in the Turkish economy has important effects on industrial production, as well as many economic variables. The main purpose of this study is to empirically analyse the effects of real effective exchange rate on industrial production for the Turkish economy in the 2009M08-2022M01 period. According to the results of the study, the real effective exchange rate adversely affects the industrial production in the Turkish economy. Other things being equal, the depreciation of the domestic currency increases the foreign demand for industrial products, in line with the economic theory. Considering these relations between real effective exchange rate and industrial production while designing economic policies is important for sustainable economic growth.
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In the real world, pathogens do not exist in isolation. The transmission of one pathogen may be affected by the presence of other pathogens, and certain pathogens generate multiple strains with different spreading features. Hence, the behavior of multi-pathogen transmission has attracted much attention in epidemiological research. In this paper, we use the pairwise approximation method to formulate two-pathogen models capturing cross-immunity, super-infection, and co-infection phenomena, in which each pathogen follows a susceptible-infected-susceptible (SIS) mechanism. For each model, we calculate the basic reproduction number and analyze the stability of equilibria, and discuss the differences from the mean-field approach. We demonstrate that simulations are in good agreement with the analytical results.
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In this paper, a discretization of a three-dimensional fractional-order prey-predator model has been investigated with Holling type III functional response. All its fixed points are determined;also, their local stability is investigated. We extend the discretized system to an optimal control problem to get the optimal harvesting amount. For this, the discrete-time Pontryagin’s maximum principle is used. Finally, numerical simulation results are given to confirm the theoretical outputs as well as to solve the optimality problem.
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PurposeThe purpose of this paper is to investigate the effects of irregular unsettling on the smoking model in form of the stochastic model as in the deterministic model these effects are neglected for simplicity.Design/methodology/approachIn this research, the authors investigate a stochastic smoking system in which the contact rate is perturbed by Lévy noise to control the trend of smoking. First, present the formulation of the stochastic model and study the dynamics of the deterministic model. Then the global positive solution of the stochastic system is discussed. Further, extinction and the persistence of the proposed system are presented on the base of the reproductive number.FindingsThe authors discuss the dynamics of the deterministic smoking model form and further present the existence and uniqueness of non-negative global solutions for the stochastic system. Some previous study’s mentioned in the Introduction can be improved with the help of obtaining results, graphically present in this manuscript. In this regard, the authors present the sufficient conditions for the extinction of smoking for reproductive number is less than 1.Research limitations/implicationsIn this work, the authors investigated the dynamic stochastic smoking model with non-Gaussian noise. The authors discussed the dynamics of the deterministic smoking model form and further showed for the stochastic system the existence and uniqueness of the non-negative global solution. Some previous study’s mentioned in the Introduction can be improved with the help of obtained results, clearly shown graphically in this manuscript. In this regard, the authors presented the sufficient conditions for the extinction of smoking, if <1, which can help in the control of smoking. Motivated from this research soon, the authors will extent the results to propose new mathematical models for the smoking epidemic in the form of fractional stochastic modeling. Especially, will investigate the effective strategies for control smoking throughout the world.Originality/valueThis study is helpful in the control of smoking throughout the world.
ABSTRACT
In this study, we are going to explore mathematically the dynamics of giving up smoking behavior. For this purpose, we will perform a mathematical analysis of a smoking model and suggest some conditions to control this serious burden on public health. The model under consideration describes the interaction between the potential smokers P, the occasional smokers L, the chain smokers S, the temporarily quit smokers QT, and the permanently quit smokers QP. Existence, positivity, and boundedness of the proposed problem solutions are proved. Local stability of the equilibria is established by using Routh–Hurwitz conditions. Moreover, the global stability of the same equilibria is fulfilled through using suitable Lyapunov functionals. In order to study the optimal control of our problem, we will take into account a two controls’ strategy. The first control will represent the government prohibition of smoking in public areas which reduces the contact between nonsmokers and smokers, while the second will symbolize the educational campaigns and the increase of cigarette cost which prevents occasional smokers from becoming chain smokers. The existence of the optimal control pair is discussed, and by using Pontryagin minimum principle, these two optimal controls are characterized. The optimality system is derived and solved numerically using the forward and backward difference approximation. Finally, numerical simulations are performed in order to check the equilibria stability, confirm the theoretical findings, and show the role of optimal strategy in controlling the smoking severity.